iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sapiens GN=STK3 PE=1 SV=2

{"length":"491","regions":[{
startStyle: "straight", endStyle: "straight",
start: 8, end: 21, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 8, end: 21}
},
{
startStyle: "curved", endStyle: "curved",
start: 27, end: 278, text: "S_TKc", colour: "#ff8800",
"metadata":{ database: "SMART", type: "S_TKc",
description: "S_TKc", start: 27, end: 278}
},
{
startStyle: "straight", endStyle: "straight",
start: 287, end: 326, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 287, end: 326}
},
{
startStyle: "curved", endStyle: "curved",
start: 436, end: 484, text: "Pfam:Mst1_SARAH", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Mst1_SARAH",
description: "Pfam:Mst1_SARAH", start: 436, end: 484}
},
{
startStyle: "straight", endStyle: "straight",
start: 25, end: 30, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:EVFDVL", start: 25, end: 30}
},
{
startStyle: "straight", endStyle: "straight",
start: 435, end: 440, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:GDFDFL", start: 435, end: 440}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	25	30	EVFDVL	9 (2.8e-01)		[+/-] 4LG4_A,B,C,D,E,F 4LGD_A,B,C,D 4LG4_A,B,C,D,E,F 4LGD_A,B,C,D 3A7H_A,B 3GUB_A 3GU8_A 1YVJ_A 3LXL_A 3LXK_A 3PJC_A 4I6Q_A 4HVI_A 4HVH_A 4HVG_A 4HVD_A 3ZEP_A,B,C,D 3ZC6_A,B,C,D 2VZ6_A,B 2WQN_A 4GL9_A,B,C,D 2WQM_A 3KCK_A 3IOK_A 3IO7_A 3JY9_A 4GMY_A 4GFM_A 4F09_A 4F08_A,B 3A7G_A,B 4E4M_A,B,D,E 4AQC_A,B 3LPB_A,B 3KRR_A 4JIA_A 4JI9_A,B 4IVA_A 4HGE_A,B 3E64_A 3E63_A 3E62_A 3TJD_A,B 3TJC_A,B 3Q32_A,B 3FUP_A,B 2XA4_A,B 2B7A_A,B 3RVG_A 2W1I_A,B 4C62_A,B 4C61_A,B 3ZMM_A,B 4B9D_A,B 3UGC_A 4APC_A,B 3A7F_A 2PE2_A 2PE1_A 2PE0_A 1Z5M_A 3Q5I_A 3NUY_A 3NUU_A 3NUS_A 1UU9_A 1UVR_A 4FZF_B 1H1W_A 4BBF_A,B,C,D 4BBE_A,B,C,D 3A4O_X 3P1A_A 4E6Q_A,B 4E6D_A,B 2ZVA_A 2ZV9_A 2ZV8_A 2ZV7_A 1UWJ_A,B 4FK3_A,B 3IDP_A,B 4G9R_A,B 4EHG_A,B 4FZD_B 3OG7_A,B 4JVG_A,B,C,D 4H58_A,B,C 4KSQ_A,B 4KSP_A,B 4FC0_A,B 4DBN_A,B 3Q96_A,B 2FB8_A,B 3C4C_A,B 4G9C_A,B 4EHE_A,B 4E4X_A,B 4E26_A,B 3TV6_A,B 3TV4_A,B 3SKC_A,B 3Q4C_A,B 3PSD_A,B 3PSB_A,B 3PRI_A,B 3PRF_A,B 3PPK_A,B 3PPJ_A,B 3D4Q_A,B 4MBJ_A,B 3II5_A,B 1UWH_A,B 4FZA_B 4J95_A,B,C,D 2PVY_A,B,C,D 4J99_A,B,C,D 4J98_A,B 2PZP_A,B 2PWL_A,B 4J97_A,B,C,D 2PZ5_A,B 3RI1_A,B 1OEC_A 1GJO_A 3B2T_A,B 4J96_A,B 3CLY_A 2PVF_A 2PZR_A,B 3QC9_A,B,C,D 2XIK_A 3C51_A,B 3C50_A,B 3C4Z_A 3C4Y_A,B 3C4X_A,B 3C4W_A,B 2PSQ_A,B 3T8O_A 1U54_A 1U54_B 1U4D_A,B 1U46_A,B 4L9I_A,B 4HZS_A,B,C,D 4EWH_A,B 3EQR_A,B 3EQP_A,B 4I22_A 4I1Z_A 4I24_A,B 3LZB_A,B,C,D,E,F,G,H 3IKA_A,B 2JIV_A,B 2JIU_A,B 2JIT_A,B 4G5P_A,B 4BC6_A 2Q0B_A,B 4ID7_A 4HZR_A,B 4EQU_A,B 3GT8_A,B,C,D 2GS7_A,B 2PY3_A,B 4AOT_A,B 4HJO_A 2OG8_A,B 4LL0_A,B 3LCK_A 3BYO_A 2OF4_A 2OF2_A 3W2R_A 3W2Q_A 3W2P_A 3W2O_A 4I21_A,B 3BYM_A 2OFU_A 2ZOQ_A,B 3VJO_A 3BEL_A 2RGP_A 4I20_A 3B2W_A 2OFV_A,B 3BYU_A 3BYS_A 1QPJ_A 1QPE_A 1QPC_A 4I23_A 3W33_A 3W32_A 3W2S_A 2RF9_A,B 2GS6_A 2GS2_A 1M17_A 1M14_A 3VJN_A 3UG2_A 3UG1_A 2J7T_A 3TT0_A,B 3KMM_A 4JRV_A 4JR3_A 4JQ8_A 4JQ7_A 1XKK_A 4NKS_A,B 4NKA_A,B 4NK9_A,B 4F65_A,B 4F64_A,B 4F63_A,B 3GQL_A,B,C 4G5J_A 4LI5_A 3POZ_A 2J6M_A 2J5F_A 2J5E_A 2ITY_A 2ITX_A 2ITW_A 2FGI_A,B 1FGK_A,B 1FGI_A,B 1AGW_A,B 3KY2_A,B 3KXZ_A 3JS2_A,B 2PL0_A 3C4F_A,B 3AD6_A 3AD5_A 3AD4_A 3ACK_A 3ACJ_A 3AC8_A 3AC5_A 3AC4_A 3AC3_A 3AC2_A 3AC1_A 2ZYB_A 2ZM4_A 2ZM1_A 3VS7_A,B 3VS6_A,B 3VS5_A,B 3VS4_A,B 3VS3_A,B 3VS2_A,B 3VS1_A,B 3VS0_A,B 3VRZ_A,B 3VRY_A,B 3RHX_A,B 2C0T_A,B 2C0O_A,B 2C0I_A,B 1QCF_A 3GQI_A 3KXX_A,B,C,D 4C3F_A 3MPM_A 4FF8_A 4FEQ_A 3QUP_A 3GOP_A 3G6H_A,B 3DQW_A,B,C,D 1QPD_A 2X7F_A,B,C,D,E 3LOK_A,B 3F3W_A,B 2QQ7_A,B 2QI8_A,B 4MXZ_A,B 4MXY_A,B 2EB3_A 2SRC_A 1Y57_A 1FMK_A 2RFE_A,B,C,D 2RFD_A,B 4FIC_A,B 4DGG_A,B 4AGW_A,B 3UQG_A,B 3UQF_A,B 3G6G_A,B 3F6X_A,B,C,D 3EN7_A,B 3EN6_A,B 3EN5_A,B 3EN4_A,B 3EL8_A,B 3EL7_A 3DQX_A,B 3D7T_B 2OIQ_A,B 4LQM_A 3U51_A,B 3U4W_A 3SVV_A,B 3QLG_A,B 3QLF_A,B 3OF0_A,B 3OEZ_A,B 2ITZ_A 2ITV_A 2ITU_A 2ITT_A 2H8H_A 2HK5_A 2PTK_A 3D7U_B,D 1KSW_A 1RJB_A 4MXO_A,B 2BDJ_A 2BDF_A,B 4MCV_A,B 1YI6_A,B 4LGH_A,B 2EB2_A 2ITQ_A 2ITP_A 2ITO_A 2ITN_A 3GEQ_A,B 2HW7_A 2AC5_A 1YOL_A,B 1YOM_A,B 1YOJ_A,B 2DQ7_X 2UV2_A 3TZ9_A,B 3TZ8_A,B 3TZ7_A,B 3G5D_A,B 3F3V_A,B 3F3U_A,B 3F3T_A,B 2QLQ_A,B 2HWP_A,B 2HWO_A,B 2HCK_A,B 1AD5_A,B 4MXX_A,B 3C7Q_A 3EFL_A,B 2P2I_A,B 3ZBF_A 4ASE_A 4ASD_A 4AGD_A 4AGC_A 3CJG_A 3CJF_A 2OH4_A 3U6J_A 4AG8_A 2XIR_A 1YWN_A 1VR2_A 3EWH_A 3DTW_A,B 3CPC_A,B 3CPB_A,B 3CP9_A,B 3BE2_A 3B8R_A,B 3B8Q_A,B 2RL5_A 2QU6_A,B 2JFM_A 2QU5_A 2P2H_A 4LRM_A,B,C,D,E 3VO3_A 3VNT_A 2AC3_A 1T46_A 4HVS_A 3G0F_A,B 1T45_A 3G0E_A 1PKG_A,B 3GB2_A 2JFL_A 2OW3_A,B 4B7T_A 3ZDI_A 3SD0_A,B 1R0E_A,B 3F7Z_A,B 4E7W_A 3ZRM_A,B 3ZRL_A,B 3ZRK_A,B 4DIT_A 3PUP_A,B 3M1S_A,B 2JLD_A,B 1J1C_A,B 1J1B_A,B 1I09_A,B 4J71_A,B 4J1R_A,B,C,D 3L1S_A,B 3I4B_A,B 1Q5K_A,B 1O9U_A 3DU8_A,B 1PYX_A,B 4AFJ_A,B 4ACH_A,B 4ACG_A,B 4ACD_A,B 4ACC_A,B 3Q3B_A,B 1Q4L_A,B 1Q41_A,B 1Q3W_A,B 1Q3D_A,B 3SAY_A,B 4IQ6_A,B 2O5K_A 1GNG_A,B 1UV5_A 3F88_A,B 1H8F_A,B 2J51_A 2Y4I_B 1LUF_A 3RP9_A 4K0Y_A 4K1B_A 3C4E_A,B,C,D 1YI4_A 1YI3_A 1YHS_A 4K18_A 3BGZ_A 3BGQ_A 3BGP_A 2OBJ_A 4BZO_A 4BZN_A 4JX7_A 4JX3_A 3A99_A 1XWS_A 4DTK_A 4I41_A 2XJ2_A 2XJ1_A 2XJ0_A 2XIZ_A 2XIY_A 2XIX_A 4N70_A 4N6Z_A 4N6Y_A 4ALW_A 4ALV_A 3T9I_A 3DCV_A 4A7C_A 3F2A_A 1XR1_A 1XQZ_A 1YXS_A 3VC4_A 3VBY_A 3VBX_A 3VBW_A 3VBV_A 3VBT_A 3VBQ_A 3R04_A 3R02_A 3R01_A 3R00_A 4ENY_A 4ENX_A 3UMX_A 3UMW_A 3UIX_A 4IAA_A 4MBL_A 4MBI_A 3JYA_A 3JY0_A 1YHW_A 3JXW_A 2O65_A 2O64_A 2O63_A 2O3P_A 1YXX_A 1YXV_A 1YXU_A,B,C,D 1YXT_A 1YWV_A 4AS0_A 4GW8_A 3QF9_A 3MA3_A 3JPV_A 2J2I_B 3CY3_A 3CY2_A 3CXW_A 3BWF_A 2OI4_X 2C3I_B 2BZK_B 2BZJ_A 2BZI_B 2BZH_B 2BIL_B 2BIK_B 4F7S_A 4F7N_A 4F7L_A 4F7J_A 4F70_A 4F6W_A 4F6U_A 4F6S_A 3RGF_A 4G6L_A 4ANS_A 4ANQ_A 4ANL_A 2YHV_A 4F9C_A 4F9B_A,C 4F9A_A,C 4F99_A 2YFX_A 1NA7_A 2YJR_A 2XBA_A 2XB7_A 2XP2_A 2YJS_A 4FNW_A 4FNY_A 4FNX_A 4FNZ_A 4FOD_A 4DCE_A,B 3AOX_A 1F3M_C,D 4JOA_A 3LCT_A 3LCS_A 4FOC_A 4FOB_A 3L9P_A 2QLU_A 4CKR_A 4BKJ_A,B 3ZOS_A,B 3BE9_A 2PVN_A 2PVM_A 2PVL_A 2PVK_A 2PVJ_A 2PVH_A 3PVG_A 4DGN_A 4ANM_A 4DGO_A 1M2P_A 3KXN_A 3KXM_A 3KXH_A 3KXG_A 1M2R_A 1M2Q_A 1DAY_A 1DAW_A 3PZH_A 3PWD_A 3FL5_A 2QC6_A 2OXY_A,B 2OXX_A 2OXD_A 1ZOH_A 1ZOG_A 1ZOE_A 1OM1_A 1LR4_A 1LPU_A 1LP4_A 1JAM_A 1J91_A,B 1F0Q_A 1DS5_A,B,C,D 3NR9_A,B,C 4DGM_A 3JUH_A,B 3RAW_A,B 2WU7_A 2WU6_A 2EU9_A 2EXE_A 4DAW_A 3U87_A,B 3WAR_A 3AXW_A 3AT4_A 3AT3_A 3AT2_A 3AMY_A 2ZJW_A 3R0T_A 3PE2_A 3PE1_A 3NSZ_A 1JWH_A,B 2PVR_A 1PJK_A 4IB5_A,B,C 4GUB_A 4GRB_A 4FBX_A 3U9C_A,B 3U4U_A 3RPS_A,B 3QA0_A,B 3Q9Z_A,B 3Q9Y_A 3Q9X_A,B 3Q9W_A 3NGA_A,B 3FWQ_A,B 3C13_A 3BQC_A 3Q04_A 3H30_A,B 2R7I_A,B,C,D 3OWL_A 3OWK_A 3OWJ_A 3MB7_A 3MB6_A 4MD7_E,F,G,H 3W8L_A,B 4MD9_E,F,G,H,K,L,M,P 4MD8_E,F,G,H 3FY0_A 3COM_A,B 3FXZ_A 4EQC_A 3Q53_A 3Q52_A 2HY8_1 1YHV_A 3Q4Z_A,B 2GCD_A,B 1U5R_A,B 1U5Q_A,B 3GGF_A,B 2F57_A,B 4APP_A 2X4Z_A 4L67_A 2BVA_A,B 2C30_A 4KS8_A 4KS7_A 2J0I_A 2CDZ_A 4GCJ_A 4EZ7_A 4EZ3_A 4ERW_A 3CKX_A 2Q0N_A 3SQQ_A 3S1H_A 3S0O_A 3S00_A 3RZB_A 3RPY_A 3RPV_A 3RPR_A 3RPO_A 3ROY_A 3RNI_A 3RMF_A 3RM7_A 3RM6_A 3RKB_A 3RK9_A 3RK7_A 3RK5_A 3RJC_A 3RAL_A 4FIJ_A 3RAK_A 3RAI_A 3RAH_A 3R9O_A 3R9N_A 3R9H_A 3R9D_A 3R8Z_A 3R8V_A 3R8U_A 4FII_A 3R8P_A 3R8M_A 3R8L_A 3R83_A 3R7Y_A 3R7V_A 3R7U_A 3R7I_A 3R7E_A 3R73_A 4FIH_A 3R71_A 3R6X_A 3R28_A 3R1Y_A 3R1S_A 3R1Q_A 3QZI_A 3QZH_A 3QZG_A 3QZF_A 4FIG_A,B 3QXP_A 3QXO_A 3QX4_A 3QX2_A 3QWK_A 3QWJ_A 3QU0_A 3QTZ_A 3QTX_A 3QTW_A 4FIF_A,B 3QTU_A 3QTS_A 3QTR_A 3QTQ_A 3QRU_A 3QRT_A 3QQL_A 3QQK_A 3QQJ_A 3QQH_A 3QQG_A 3QQF_A 3QL8_A 3PY1_A 3PY0_A 3PXZ_A 3PXY_A 3PXR_A 3PXQ_A 3PXF_A 4FIE_A,B 3CKW_A 3ZHP_C,D 3MFU_A 3MFT_A 3MFS_A 3MFR_A 3A7J_A 3IS5_A,B,C,D,E,F 2YAB_A,B 2YAA_A,B 2YA9_A,B 1CM8_A,B 2CKE_A,B,C,D 2A2A_A,B,C,D 1Z9X_A,B,C 2JC6_A,C 2F2C_B 2EUF_B 1XO2_B 1JOW_B 2A27_A,B,C,D,E,F,G,H 1WMK_A,B,C,D,E,F,G,H 4EZ5_A 4AUA_A 3NUX_A 3NUP_A 1G3N_A,E 1BLX_A 1BI8_A,C 1BI7_A 1ZWS_A,B,C,D,E,F,G,H 3TAC_A 3A7I_A 1KOB_A,B 4BBM_A,B 4AAA_A 3C0I_A 3C0H_A,B 3C0G_A,B 2J90_A,B 3BQR_A 3BHY_A 2XUU_A 1YRP_A,B 2Y0A_A 4B4L_A 2X0G_A 2W4J_A 1WVY_A 1WVX_A 1WVW_A 2XZS_A,B 3ZXT_A,B,C,D 2YAK_A 2Y4P_A,B,C,D 1P4F_A 2W4K_A 3F5G_A 3EHA_A 3EH9_A 1JKT_A,B 1JKS_A 1JKL_A 1JKK_A 1IG1_A 3GU7_A 3GU6_A 3GU5_A 3GU4_A 3F5U_A 3DGK_A 3DFC_B	No
xLIR	435	440	GDFDFL	16 (3.0e-02)	CALR_HUMAN 198-203 (4)	4LGD_A,B,C,D	Yes

[+/-] Show/Hide Detailed ANCHOR results

DOMAIN	START	END	STATUS
ANCHOR1	251	259	hidden
ANCHOR2	272	298	hidden
ANCHOR3	321	369	hidden
ANCHOR4	389	402	hidden
ANCHOR5	436	455	hidden

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
low_complexity_region	8	21	0	INTRINSIC	visible\|OK
SMART:S_TKc	27	278	3.1e-103	SMART	visible\|OK
Pfam:Pkinase_Tyr	27	275	2.8e-53	PFAM	hidden\|overlap
Pfam:Pkinase	27	278	2.3e-71	PFAM	hidden\|overlap
coiled_coil_region	287	326	0	INTRINSIC	visible\|OK
low_complexity_region	301	324	0	INTRINSIC	hidden\|overlap
Pfam:Mst1_SARAH	436	484	2.0e-29	PFAM	visible\|OK