iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|Q14596|NBR1_HUMAN Next to BRCA1 gene 1 protein OS=Homo sapiens GN=NBR1 PE=1 SV=3

{"length":"966","regions":[{
startStyle: "curved", endStyle: "curved",
start: 4, end: 85, text: "PB1", colour: "#00ff00",
"metadata":{ database: "SMART", type: "PB1",
description: "PB1", start: 4, end: 85}
},
{
startStyle: "straight", endStyle: "straight",
start: 98, end: 112, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 98, end: 112}
},
{
startStyle: "curved", endStyle: "curved",
start: 211, end: 256, text: "ZnF_ZZ", colour: "#00ff00",
"metadata":{ database: "SMART", type: "ZnF_ZZ",
description: "ZnF_ZZ", start: 211, end: 256}
},
{
startStyle: "straight", endStyle: "straight",
start: 288, end: 329, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 288, end: 329}
},
{
startStyle: "straight", endStyle: "straight",
start: 693, end: 728, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 693, end: 728}
},
{
startStyle: "straight", endStyle: "straight",
start: 805, end: 822, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 805, end: 822}
},
{
startStyle: "straight", endStyle: "straight",
start: 561, end: 566, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:LSFELL", start: 561, end: 566}
},
{
startStyle: "straight", endStyle: "straight",
start: 730, end: 735, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:EDYIII", start: 730, end: 735}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	561	566	LSFELL	10 (2.0e-01)			Yes
xLIR	730	735	EDYIII	17 (2.2e-02)	NBR1_HUMAN 730-735 (6) TBC25_HUMAN 134-139 (4)		Yes

[+/-] Show/Hide Detailed ANCHOR results

DOMAIN	START	END	STATUS
ANCHOR01	36	45	hidden
ANCHOR02	110	122	hidden
ANCHOR03	135	140	hidden
ANCHOR04	154	160	hidden
ANCHOR05	322	335	hidden
ANCHOR06	357	373	hidden
ANCHOR07	472	478	hidden
ANCHOR08	547	571	hidden
ANCHOR09	616	623	hidden
ANCHOR10	643	662	hidden
ANCHOR11	672	703	hidden
ANCHOR12	719	767	hidden
ANCHOR13	769	782	hidden
ANCHOR14	793	847	hidden

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
SMART:PB1	4	85	1.4e-14	SMART	visible\|OK
Pfam:PB1	4	85	5.6e-15	PFAM	hidden\|overlap
low_complexity_region	98	112	0	INTRINSIC	visible\|OK
SMART:ZnF_ZZ	211	256	5.3e-15	SMART	visible\|OK
Pfam:ZZ	212	253	1.8e-09	PFAM	hidden\|overlap
coiled_coil_region	288	329	0	INTRINSIC	visible\|OK
low_complexity_region	688	720	0	INTRINSIC	hidden\|overlap
coiled_coil_region	693	728	0	INTRINSIC	visible\|OK
low_complexity_region	805	822	0	INTRINSIC	visible\|OK