iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|Q9BQS8|FYCO1_HUMAN FYVE and coiled-coil domain-containing protein 1 OS=Homo sapiens GN=FYCO1 PE=1 SV=3

{"length":"1478","regions":[{
startStyle: "curved", endStyle: "curved",
start: 12, end: 168, text: "Pfam:RUN", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:RUN",
description: "Pfam:RUN", start: 12, end: 168}
},
{
startStyle: "straight", endStyle: "straight",
start: 196, end: 207, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 196, end: 207}
},
{
startStyle: "straight", endStyle: "straight",
start: 225, end: 280, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 225, end: 280}
},
{
startStyle: "straight", endStyle: "straight",
start: 336, end: 363, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 336, end: 363}
},
{
startStyle: "straight", endStyle: "straight",
start: 394, end: 557, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 394, end: 557}
},
{
startStyle: "straight", endStyle: "straight",
start: 596, end: 1151, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 596, end: 1151}
},
{
startStyle: "curved", endStyle: "curved",
start: 1165, end: 1232, text: "FYVE", colour: "#ff8800",
"metadata":{ database: "SMART", type: "FYVE",
description: "FYVE", start: 1165, end: 1232}
},
{
startStyle: "straight", endStyle: "straight",
start: 1249, end: 1262, text: "LCR", colour: "#86bcff",
"metadata":{ database: "INTRINSIC", type: "low_complexity_region",
description: "LCR", start: 1249, end: 1262}
},
{
startStyle: "straight", endStyle: "straight",
start: 644, end: 649, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:ADYQAL", start: 644, end: 649}
},
{
startStyle: "straight", endStyle: "straight",
start: 1278, end: 1283, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:AVFDII", start: 1278, end: 1283}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	644	649	ADYQAL	15 (4.2e-02)			Yes
xLIR	1278	1283	AVFDII	8 (3.9e-01)	FYCO1_HUMAN 1278-1283 (6)		Yes

[+/-] Show/Hide Detailed ANCHOR results

DOMAIN	START	END	STATUS
ANCHOR01	289	298	hidden
ANCHOR02	317	324	hidden
ANCHOR03	336	348	hidden
ANCHOR04	363	378	hidden
ANCHOR05	402	408	hidden
ANCHOR06	544	564	hidden
ANCHOR07	566	584	hidden
ANCHOR08	638	646	hidden
ANCHOR09	677	685	hidden
ANCHOR10	768	774	hidden
ANCHOR11	814	820	hidden
ANCHOR12	841	848	hidden
ANCHOR13	907	916	hidden
ANCHOR14	925	930	hidden
ANCHOR15	968	978	hidden
ANCHOR16	1001	1014	hidden
ANCHOR17	1062	1075	hidden
ANCHOR18	1272	1298	hidden
ANCHOR19	1307	1312	hidden
ANCHOR20	1334	1353	hidden

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
coiled_coil_region	4	33	0	INTRINSIC	hidden\|overlap
Pfam:RUN	12	168	4.2e-12	PFAM	visible\|OK
low_complexity_region	196	207	0	INTRINSIC	visible\|OK
coiled_coil_region	225	280	0	INTRINSIC	visible\|OK
coiled_coil_region	336	363	0	INTRINSIC	visible\|OK
coiled_coil_region	394	557	0	INTRINSIC	visible\|OK
low_complexity_region	427	439	0	INTRINSIC	hidden\|overlap
low_complexity_region	484	507	0	INTRINSIC	hidden\|overlap
coiled_coil_region	596	1151	0	INTRINSIC	visible\|OK
low_complexity_region	639	651	0	INTRINSIC	hidden\|overlap
low_complexity_region	686	700	0	INTRINSIC	hidden\|overlap
low_complexity_region	763	779	0	INTRINSIC	hidden\|overlap
low_complexity_region	854	877	0	INTRINSIC	hidden\|overlap
low_complexity_region	885	899	0	INTRINSIC	hidden\|overlap
low_complexity_region	953	996	0	INTRINSIC	hidden\|overlap
SMART:FYVE	1165	1232	1.0e-21	SMART	visible\|OK
Pfam:FYVE	1168	1232	1.9e-18	PFAM	hidden\|overlap
low_complexity_region	1231	1247	0	INTRINSIC	hidden\|overlap
low_complexity_region	1249	1262	0	INTRINSIC	visible\|OK