iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|P40939|ECHA_HUMAN Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens GN=HADHA PE=1 SV=2

{"length":"763","regions":[{
startStyle: "curved", endStyle: "curved",
start: 50, end: 223, text: "Pfam:ECH", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:ECH",
description: "Pfam:ECH", start: 50, end: 223}
},
{
startStyle: "curved", endStyle: "curved",
start: 363, end: 542, text: "Pfam:3HCDH_N", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:3HCDH_N",
description: "Pfam:3HCDH_N", start: 363, end: 542}
},
{
startStyle: "curved", endStyle: "curved",
start: 544, end: 639, text: "Pfam:3HCDH", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:3HCDH",
description: "Pfam:3HCDH", start: 544, end: 639}
},
{
startStyle: "curved", endStyle: "curved",
start: 673, end: 760, text: "Pfam:3HCDH", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:3HCDH",
description: "Pfam:3HCDH", start: 673, end: 760}
},
{
startStyle: "straight", endStyle: "straight",
start: 447, end: 452, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:AVFEDL", start: 447, end: 452}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	447	452	AVFEDL	7 (5.3e-01)		[+/-] 2D3T_A,B 1WDM_A,B 2D3T_A,B 1WDM_A,B 3ZWA_A,B 3ZW9_A,B 3ZW8_A,B 3F3S_A,B 3ZWB_A,B 3K6J_A 1ZCJ_A 1M75_A,B 3RQS_A,B 1F0Y_A,B 3HAD_A,B 1WDL_A,B 1LSO_A,B 2HDH_A,B 1LSJ_A,B 1IL0_A,B 1M76_A,B 1F17_A,B 1F14_A,B 1F12_A,B 3HDH_A,B,C 1WDK_A,B 3MOG_A,B,C 1ZEJ_A 4B3J_A,B 4B3I_A,B 4B3H_A,B 4E13_A 4E12_A 4DYD_A 2WTB_A 2X58_A,B 3ZWC_A,B	No

No ANCHORs detected ...

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DOMAIN	START	END	E-VALUE	TYPE	STATUS
Pfam:ECH	50	223	2.8e-63	PFAM	visible\|OK
coiled_coil_region	111	132	0	INTRINSIC	hidden\|overlap
low_complexity_region	223	234	0	INTRINSIC	hidden\|overlap
Pfam:3HCDH_N	363	542	4.4e-56	PFAM	visible\|OK
low_complexity_region	364	377	0	INTRINSIC	hidden\|overlap
Pfam:3HCDH	544	639	6.2e-29	PFAM	visible\|OK
Pfam:3HCDH	673	760	1.1e-06	PFAM	visible\|OK
low_complexity_region	706	720	0	INTRINSIC	hidden\|overlap