iLIR v1.0 WWW Server: RESULTS PAGE

Submitted 1 sequence
>sp|P27797|CALR_HUMAN Calreticulin OS=Homo sapiens GN=CALR PE=1 SV=1 (Motif position in paper refers to mature protein chain)

{"length":"417","regions":[{
startStyle: "curved", endStyle: "curved",
start: 1, end: 17, text: "signal_peptide", colour: "#ff8800",
"metadata":{ database: "INTRINSIC", type: "signal_peptide",
description: "signal_peptide", start: 1, end: 17}
},
{
startStyle: "curved", endStyle: "curved",
start: 21, end: 332, text: "Pfam:Calreticulin", colour: "#ff8800",
"metadata":{ database: "PFAM", type: "Pfam:Calreticulin",
description: "Pfam:Calreticulin", start: 21, end: 332}
},
{
startStyle: "straight", endStyle: "straight",
start: 348, end: 408, text: "CC", colour: "#9cff00",
"metadata":{ database: "INTRINSIC", type: "coiled_coil_region",
description: "CC", start: 348, end: 408}
},
{
startStyle: "straight", endStyle: "straight",
start: 107, end: 112, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:GGYVKL", start: 107, end: 112}
},
{
startStyle: "straight", endStyle: "straight",
start: 166, end: 171, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:DEFTHL", start: 166, end: 171}
},
{
startStyle: "straight", endStyle: "straight",
start: 198, end: 203, text: "xLIR", colour: "#ff00ff",
lineStyle: "bold", v_align: "top", label: "xLIR",
"metadata":{ database: "xLIR web server", type: "xLIR-motif",
description: "xLIR-motif:DDWDFL", start: 198, end: 203}
},
]
}

xLIR motifs are displayed as magenta rectangles in the domain architecture graphic

MOTIF	START	END	LIR sequence	PSSM score	Similar LIRs	In PDB	Anchor
xLIR	107	112	GGYVKL	12 (1.1e-01)		[+/-] 3RG0_A 3POW_A 3RG0_A 3POW_A 1JHN_A 3POS_A,B,C 3O0X_A,B 3O0W_A 3O0V_A	No
xLIR	166	171	DEFTHL	14 (5.7e-02)	SQSTM_HUMAN 336-341 (4)	[+/-] 3RG0_A 3POW_A 3RG0_A 3POW_A 1JHN_A 3POS_A,B,C 3O0X_A,B 3O0W_A 3O0V_A	Yes
xLIR	198	203	DDWDFL	26 (1.2e-03)	CALR_HUMAN 198-203 (6) CLH1_HUMAN 512-517 (4) SQSTM_HUMAN 336-341 (4)	[+/-] 3RG0_A 3POW_A 3RG0_A 3POW_A 1JHN_A 3POS_A,B,C 3O0X_A,B 3O0W_A 3O0V_A	Yes

[+/-] Show/Hide Detailed ANCHOR results

DOMAIN	START	END	STATUS
ANCHOR1	170	176	hidden
ANCHOR2	198	204	hidden
ANCHOR3	259	269	hidden
ANCHOR4	304	352	hidden
ANCHOR5	409	417	hidden

[+/-] Show/Hide Detailed SMART results

DOMAIN	START	END	E-VALUE	TYPE	STATUS
signal_peptide	1	17	0	INTRINSIC	visible\|OK
low_complexity_region	2	21	0	INTRINSIC	hidden\|overlap
Pfam:Calreticulin	21	332	2.4e-127	PFAM	visible\|OK
low_complexity_region	250	264	0	INTRINSIC	hidden\|overlap
coiled_coil_region	348	408	0	INTRINSIC	visible\|OK
low_complexity_region	358	408	0	INTRINSIC	hidden\|overlap